N-CARBETHOXY-4-AMINO PIPERIDINE

PRODUCT IDENTIFICATION
CAS NO. 58859-46-4

N-CARBETHOXY-4-AMINO PIPERIDINE

EINECS NO. 261-472-3
FORMULA C8H16N2O2
MOL WT. 172.23

H.S. CODE

  

TOXICITY

 
SYNONYMS Ethyl 4-amino-1-piperidinecarboxylate;
4-Aminopiperidina-1-carboxilato de etilo; 4-Aminopipéridine-1-carboxylate d'éthyle; Ethyl  4-aminopiperidine-1-carboxylate;
DERIVATION

 

CLASSIFICATION

  

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE clear to yellowish liquid
MELTING POINT  
BOILING POINT 102 C at 102 mmHg
SPECIFIC GRAVITY 1.07
SOLUBILITY IN WATER 500 g/l at 20 C (soluble in common organic solvents)
pH  
VAPOR DENSITY

 

AUTOIGNITION

 

NFPA RATINGS

 Health: 1; Flammability: 3; Reactivity: 0

REFRACTIVE INDEX

 1.481 - 1.483
FLASH POINT

78 C

STABILITY

Stable under ordinary conditions.

GENERAL DESCRIPTION & APPLICATIONS
Piperidine, hexahydropyridine, is a family of heterocyclic organic compound derived from pyridine through hydrogenation. It has one nitrogen atom in the cycle. It is a clear liquid with pepper-like aroma. It boils at 106 C, soluble in water, alcohol, and ether. The major application of piperidine is for the production of Dipiperidinyl dithium tetrasulfide used as a rubber vulcanization accelerator. In pharmaceutical synthesis industry, it is used as a special solvent and a protecting group for peptide synthesis. Piperidine derivative compounds are used as intermediate to make crystal derivative of aromatic nitrogen compounds containing nuclear halogen atoms. Ring system compounds with nitrogen which have basic property play important roles as cyclic component in industrial field such as raw materials for hardener of epoxy resins, corrosion inhibitors, insecticides, accelerators for rubber, urethane catalysts, antioxidants and as a catalyst for silicone esters. They are used in manufacturing pharmaceuticals.

2-Piperidone, a keto-hydropyridine, is a 6-membered lactam structure compound (delta-valerolactam).  Lactam structure compounds including delta-valerolactam are good organic solvents soluble in water. Cyclic amides and analogues including N-alkyl lactams are biologically active nucleuses in pharmacologicals and flavorings. Lactams are widely used in artificial fibre industry. They are polymerizable and used as nylon precursors. They have excellent applications as solvents and as intermediates for organic synthesis. They are used in the aqueous carrier medium and amide penetrants in inks and water soluble paints. 4-Piperidone, a cyclic amide with ketone at para position, and its N-alkyl substituted derivatives are used in:

  • Alkene formation at the position of former carbonyl group. Alkene bonds are abundant in natural compounds
  • Sulfur compound removals
  • UV stabilizer products
  • Multicyclic hetero compounds and fused ring system compounds
  • Pharmaceutical synthesis including narcotic analgesics and digestive system drugs
SALES SPECIFICATION

APPEARANCE

 clear to yellowish liquid

ASSAY

98.5% min

MOISTURE

 0.5% max
TRANSPORTATION
PACKING
 
HAZARD CLASS  
UN NO.  
OTHER INFORMATION
Hazard Symbols: XI, Risk Phrases: 36/37/38, Safety Phrases: 26-3/30
PRICE
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